31 citations,
March 2018 in “Frontiers in Immunology” The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.
12 citations,
June 2020 in “Lupus” Early treatment with the right dose of stem cells can reduce lupus symptoms.
9 citations,
January 2020 in “Rheumatology Advances in Practice” SLE is rare in Uganda but often has complications and overlaps with rheumatoid arthritis.
2 citations,
December 2023 in “Mediterranean Journal of Rheumatology” Late onset SLE has different symptoms and antibody profiles compared to young onset SLE.
1 citations,
January 2022 in “Open Access Macedonian Journal of Medical Sciences” A child with low platelets and anemia was later found to have lupus.
April 2023 in “Research Square (Research Square)” Lower GPX4 mRNA levels are linked to higher disease activity and symptoms in lupus patients.
No single biomarker is reliable enough for diagnosing and assessing SLE.
August 2021 in “BMJ Case Reports” A woman with lupus had blood cell destruction, treated successfully with medication.
January 2020 in “SSRN Electronic Journal” Different autoantibody groups in pediatric SLE are linked to specific symptoms and disease outcomes.
Juvenile-onset lupus patients have more severe symptoms and need stronger treatment.
January 2014 in “Journal of Jilin University” Higher levels of certain immune cells and proteins are linked to more severe lupus symptoms.
February 2021 in “Indonesian Journal of Perinatology” Most pregnancies with SLE resulted in intrauterine growth restriction (IUGR).
February 2018 in “Chin J Clinicians(Electronic Edition)” Rash in SLE patients indicates more severe disease.
May 2018 in “The Journal of Immunology” A(1-7) treatment reduces symptoms of lupus in mice.
3 citations,
June 2020 in “Open access rheumatology” A patient with Rhupus was diagnosed with Rowell syndrome and treated with various medications.
Early identification of lupus through skin signs and blood tests is crucial in India.
3 citations,
November 2022 in “The Egyptian Rheumatologist” Macrophage activation syndrome can be a deadly first sign of systemic lupus erythematosus.
3 citations,
February 2020 in “The Egyptian Rheumatologist” Recognizing LET and AITD can help diagnose SLE early for better treatment.
278 citations,
March 2013 in “Gut” Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.
60 citations,
September 2013 in “Alimentary Pharmacology & Therapeutics” Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.
June 2020 in “Annals of the Rheumatic Diseases” Patients with Systemic Sclerosis have much higher levels of GDF-15, which could help predict organ involvement and guide treatment.
17 citations,
April 2013 in “Experimental and Therapeutic Medicine” Anti-SSB antibodies are useful for diagnosing systemic lupus erythematosus and are linked to specific symptoms.
15 citations,
January 2014 in “Anais Brasileiros de Dermatologia” Lupus treatment requires a combination of drugs and therapies, with research needed for new options.
December 2023 in “Curēus” A woman with lupus had rare severe symptoms but improved with treatment.
August 2018 in “International Journal of Research in Dermatology” Skin issues like hair loss, rash, and sensitivity to sunlight are key signs of lupus activity.
16 citations,
August 2011 in “Annals of Allergy Asthma & Immunology” A woman with severe angioedema improved significantly after treatment with rituximab.
15 citations,
March 2021 in “Journal of clinical medicine” Biologic treatments for Crohn's disease and ulcerative colitis can cause skin problems, and doctors should adjust treatment if these occur.
6 citations,
April 2020 in “Cureus” A woman with both TLE and SLE improved with hydroxychloroquine treatment.
2 citations,
January 2004 in “Elsevier eBooks” Lupus affects the skin in various ways, and proper skin examination is crucial for diagnosis and treatment.
1 citations,
January 2021 in “Arthritis Research & Therapy” About 8% of people with systemic lupus erythematosus have chronic scarring alopecia, with certain symptoms and positive antibodies increasing the risk, while immunosuppressants may lower it.