Serum Markers of Thrombophilia in Pregnant Women with Systemic Lupus Erythematosus

The study investigated the prevalence of serum markers for hereditary and acquired thrombophilia in pregnant women with Systemic Lupus Erythematosus (SLE). It included 25 pregnant women with SLE and 32 pregnant controls without known disease. The findings revealed that 72.0% of the women with SLE had thrombophilia, significantly higher than the 6.0% in the control group. The relative risks for antiphospholipid antibodies and hereditary thrombophilia in the SLE group were 13.20 and 7.26, respectively. The study concluded that pregnant women with SLE have a higher risk of obstetric complications due to the significant association with serum markers for thrombophilia.