Possible Protective Effect of Hydroxychloroquine on Delaying the Occurrence of Integument Damage in Lupus: Data from a Multiethnic Cohort

    January 2010 in “ Arthritis Care & Research ”
    Guillermo J. Pons‐Estel, Graciela S. Alarcón, Luis Alonso González, Jie Zhang, Luis M. Vilá, John D. Reveille, Gerald McGwin
    TLDR Hydroxychloroquine may help delay skin damage in lupus patients.
    The study investigated the potential protective effect of hydroxychloroquine (HCQ) on delaying integument damage, such as alopecia, in 580 multiethnic patients with systemic lupus erythematosus (SLE) over an average disease duration of 5.9 years. It found that HCQ use was associated with a longer time to integument damage, with 5% of HCQ-takers developing damage at five years compared to 24% of non-takers. Higher disease activity and certain ethnicities (Texan-Hispanic and Caucasian) were also linked to the timing of damage onset. The study suggested HCQ could be beneficial in managing SLE-related integument damage and recommended further research into other environmental factors.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 7 results

      community TE turned into Scarring hairloss

      in Update  12 upvotes 7 months ago
      The user experienced hair loss due to a crash diet and later developed scarring hair loss. They are now on finasteride, oral minoxidil, LDN, Zyrtec, and Oztela to reduce scalp inflammation and promote hair regrowth.

      community Making the jump to hair systems

      in Hair Systems  28 upvotes 3 years ago
      19-year-old with Lichen Planopilaris tried various treatments unsuccessfully. Now considering hair systems, seeking experiences and opinions.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 1 month ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community Fibrosing alopecia in a pattern distribution

      in Research/Science  14 upvotes 6 months ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

      community 5mg oral minoxidil + 100mg Spironolactone

      in Progress Pictures  10 upvotes 9 months ago
      A user shared progress pictures using 5mg oral minoxidil and 100mg spironolactone, noting increased body hair and faster nail growth. Another user humorously suggested a new sub for people with similar experiences.

    Related Research

    1 / 1 results