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    A Functional Polymorphism in Interleukin-1α (IL1A) Gene Is Associated with Risk of Alopecia Areata in Chinese Populations

    March 2013 in “ Gene ”
    Dujuan Lu, Lingling Chen, Xiaolu Shi … Xingqi Zhang
    Studysummary This study reported that the IL1A 4-bp indel polymorphism is associated with a reduced risk of alopecia areata in Chinese populations, possibly through miR-122 mediated regulation of IL-1α expression.
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    Research cited in this study 7

    1. Genetic Association of HLA-DQB1 and HLA-DRB1 Polymorphisms with Alopecia Areata in the Italian Population British Journal of Dermatology · 2011
    2. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010
    3. Alopecia Areata: Evidence-Based Treatments Seminars in cutaneous medicine and surgery · 2009
    4. Human Leukocyte Antigen Class II Alleles Are Associated with Risk of Alopecia Areata Journal of Investigative Dermatology · 2007
    5. Alopecia Areata: Overview and Treatment Options International Journal of Dermatology · 2007
    6. Alopecia Areata: A Tissue-Specific Autoimmune Disease of the Hair Follicle Autoimmunity Reviews · 2005
    7. Role of the Autoimmune Regulator (AIRE) Gene in Alopecia Areata: Strong Association of a Potentially Functional AIRE Polymorphism With Alopecia Universalis Tissue Antigens · 2002