TLDR Skin problems are common in lupus patients and should be treated early to prevent worsening.
The document reviews the skin manifestations of Systemic Lupus Erythematosus (SLE), a chronic autoimmune disease affecting 70% to 85% of patients. Skin diseases in SLE are classified as SLE-specific or SLE-nonspecific based on histopathologic findings. Acute cutaneous lupus erythematosus (ACLE) occurs in 30-50% of SLE patients, often flaring with other organ disease activity. Non-scarring alopecia, a form of hair loss, is seen in 40-70% of patients. The review emphasizes the importance of early recognition and treatment of these symptoms to prevent disease progression, with antimalarials being first-line therapies for cutaneous disease in SLE. Other treatment options include immunosuppressives, thalidomide, lenalidomide, and dapsone. The document also highlights the use of the Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) and SLEDAI 2000 (SLEDAI-2K) for disease monitoring.
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39 citations
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October 2018 in “Lupus Science & Medicine” Different types of hair loss in lupus need careful diagnosis for proper treatment.
35 citations
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January 2013 in “Dermatologic Clinics” Autoimmune diseases can cause hair loss, and early treatment is important to prevent permanent damage.
157 citations
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August 2010 in “Lupus” The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.
144 citations
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September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
148 citations
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June 2005 in “Autoimmunity Reviews” Most people with systemic lupus erythematosus have skin problems, and skin symptoms are often the first sign of the disease.
127 citations
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September 1996 in “British Journal of Dermatology” Skin problems are very common in people with systemic lupus erythematosus and important for diagnosis.
11 citations
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September 2022 in “The Journal of Rheumatology” Skin problems are common in lupus patients and should be treated early to prevent worsening.
46 citations
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June 2018 in “American Journal of Clinical Dermatology” Hair loss is common in lupus patients and can be permanent or reversible, depending on the type, with various treatments available.
144 citations
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September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
