Life-Threatening Macrophage Activation Syndrome as the Initial Presentation of Systemic Lupus Erythematosus: A Case Report and Review of the Literature
November 2022
in “
The Egyptian Rheumatologist
”
New to Prednisolone? There is a guide in the encyclopedia. Read the guide → macrophage activation syndrome systemic lupus erythematosus hair loss leucopenia neutropenia lymphopenia anemia thrombocytopenia elevated liver enzymes hyperbilirubinemia hypertriglyceridemia hyperferritinemia elevated D-Dimer elevated lactate dehydrogenase ANA anti-dsDNA low serum C3 low serum C4 methylprednisolone prednisolone cyclosporine A intravenous immunoglobulin MAS SLE low white blood cells low neutrophils low lymphocytes low red blood cells low platelets high liver enzymes high bilirubin high triglycerides high ferritin high D-Dimer high LDH antinuclear antibodies anti-double stranded DNA low C3 low C4 IV methylprednisolone IVIG
Studysummary This case report describes a rare instance where a young woman initially presented with macrophage activation syndrome as the first sign of systemic lupus erythematosus, and ultimately experienced multiorgan failure and death.
Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer