31 citations,
March 2018 in “Frontiers in Immunology” The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.
3 citations,
June 2020 in “Open access rheumatology” A patient with Rhupus was diagnosed with Rowell syndrome and treated with various medications.
2 citations,
January 2012 in “PubMed” The study evaluated the efficacy of mycophenolate mofetil (MMF) in treating juvenile onset severe lupus nephritis. Twelve children (mean age 12.6 years) underwent 6 months of induction therapy with MMF and prednisolone, resulting in significant improvements in urine protein, serum anti-double-stranded DNA antibody, renal function, albumin, and serum C3 and C4 levels (p < 0.05). Ten children continued with 18 months of maintenance therapy, during which no renal flares occurred, and the mean prednisolone dose was reduced to 9.2 mg/day. Among 5 patients who had a second biopsy, 4 showed significant histological improvement. Major infections were reported in 5 patients, including Herpes zoster, bacteremia, and hair loss. MMF was concluded to be an effective therapy for this condition.
3 citations,
January 2023 in “The Egyptian Rheumatologist” Macrophage activation syndrome can be a deadly first sign of systemic lupus erythematosus.
1 citations,
December 2021 in “Journal of the American Academy of Dermatology” Careful histologic examination is crucial to differentiate types of bullous lesions in cutaneous lupus erythematosus.