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GlossaryCyclosporine

immunosuppressive drug used to prevent organ rejection and treat autoimmune diseases

Cyclosporine, also known as cyclosporin A or CsA, is an immunosuppressive drug primarily used to prevent organ transplant rejection and to treat certain autoimmune conditions. It works by inhibiting the activity of T-cells, a type of white blood cell involved in the immune response. In dermatology, cyclosporine has been explored for its potential to treat severe cases of alopecia areata, a condition characterized by sudden hair loss.

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Identifying Novel Strategies for Treating Human Hair Loss Disorders: Cyclosporine A Suppresses the Wnt Inhibitor, SFRP1, in the Dermal Papilla of Human Scalp Hair Follicles

research Identifying Novel Strategies for Treating Human Hair Loss Disorders: Cyclosporine A Suppresses the Wnt Inhibitor, SFRP1, in the Dermal Papilla of Human Scalp Hair Follicles

68 citations, May 2018 in “PLOS Biology”

Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.

research Cyclosporine for Moderate-to-Severe Alopecia Areata: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial of Efficacy and Safety

44 citations, April 2019 in “Journal of the American Academy of Dermatology”

Cyclosporine showed some improvement in alopecia areata but results were not statistically significant.

research Efficacy of Combined Cyclosporine A and Ketoconazole Treatment of Anal Furunculosis

36 citations, May 2004 in “The journal of small animal practice/Journal of small animal practice”

Combining cyclosporine A and ketoconazole can effectively treat anal furunculosis in dogs, with some experiencing recurrences and mild side effects.

Chemotherapy-Induced Alopecia in Mice: Induction by Cyclophosphamide, Inhibition by Cyclosporine A, and Modulation by Dexamethasone

research Chemotherapy-Induced Alopecia in Mice: Induction by Cyclophosphamide, Inhibition by Cyclosporine A, and Modulation by Dexamethasone

36 citations, April 1994 in “PubMed”

Cyclosporine A slows down hair loss from chemotherapy in mice, while dexamethasone increases hair loss but speeds up regrowth.

research Effects of Cyclosporine A on Clinical and Histologic Abnormalities in Dogs with Sebaceous Adenitis

34 citations, January 2005 in “Journal of the American Veterinary Medical Association”

Cyclosporine A can reduce inflammation in dogs with sebaceous adenitis, but ongoing treatment is needed.

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community Why isn't anyone using Way-316606? If it works then it grows a full head of hair back on most people

in Treatment 134 upvotes 3 weeks ago

Way-316606 is considered a potential hair loss treatment but is avoided due to safety concerns and lack of research. Minoxidil and Finasteride are preferred as established treatments.

community Huge Group Buy is Now Live with New and Existing Treatments

in Product 146 upvotes 1 year ago

A group buy for hair loss treatments including Harmine 19a, TM5614, Abiraterone Acetate, and others. A compound, BMS-202, that can potentially reverse gray hair is also mentioned.

community Starting Way-316606 for the first time today.

in Research/Science 31 upvotes 2 weeks ago

A user is experimenting with a homemade solution of WAY-316606 for hair regrowth, combining it with other treatments like minoxidil and dutasteride. The community expresses concern over the safety and mental health implications of such drastic measures, with mixed opinions on the effectiveness of WAY-316606.

community The most nuclear stack possible

in Satire 36 upvotes 6 days ago

A user humorously suggests an extreme hair loss treatment regimen involving multiple medications and therapies, including Dutasteride, Minoxidil, RU58841, and others, claiming it would prevent hair loss but with potential side effects like gynecomastia. The conversation highlights concerns about safety, side effects, and the effectiveness of such a comprehensive approach.

community Is itching related to hair loss?

in Treatment 54 upvotes 2 years ago

Hair loss, which is sometimes accompanied by itching. Treatments discussed include Minoxidil, finasteride, RU58841 and ketocazole shampoo.

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