research Animal Models of Psoriasis: What Can We Learn from Them?
Rodent models helped understand psoriasis but none perfectly replicated the disease.
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research Alopecia Areata: Animal Models Illuminate Autoimmune Pathogenesis and Novel Immunotherapeutic Strategies
Animal models have helped understand hair loss from alopecia areata and find new treatments.
research Animal Models for the Study of Fetal Tissue Repair
Understanding how fetal wounds heal could help improve healing in adults.
research Animal Models of Psoriasis: Highlights and Drawbacks
Animal models help study psoriasis but have limitations and don't fully mimic the human disease.
research Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction
High levels of androgens during early development may cause PCOS-like symptoms.
research Animal Models of Androgen-Dependent Disorders of the Pilosebaceous Apparatus
Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
research Hair Loss And Regeneration Performed On Animal Models
Animal models are crucial for learning about hair loss and finding treatments.
research Animal Models and Culture Methods in the Study of Hair Growth
The new microneedle method delivers hair loss treatment more effectively by enhancing growth pathways.
research Animal Models of Alopecia
The best animal model for studying male-pattern baldness is the stumptailed macaque, not rats or mice.
research Animal Models for Male Pattern (Androgenetic) Alopecia
The stump-tailed macaque is a good model for studying human hair loss, but it's expensive and hard to find, while rodent models are promising for understanding hair growth and finding new treatments.
research Animal Models for Wound Healing
Animal experiments help understand and test treatments for healing wounds and reducing scars.
research Evaluation of Animal Models Suitable for Hair Research and Regeneration
Animal models, especially mice, are essential for advancing hair loss research and treatment.
research Analysis of Animal Models of Alopecia Areata Based on Clinical Features of Traditional Chinese and Western Medicine
Better models and evaluation methods for alopecia areata are needed.
research Animal and In Vitro Models for the Study of Hair Follicles
The document reviewed various in vitro and in vivo models used to study hair follicles, emphasizing their role in understanding the complex biological mechanisms and hormonal control of hair growth. It highlighted the differences in human hair growth compared to other mammals, particularly in response to androgens. Animal models like Wistar rats, C57BL/6 mice, and androgen-sensitive animals such as hamsters were used, though each had limitations. The research underscored the importance of dermal papilla cells and conditioned media in studying mesenchyme-epithelial interactions and androgen action. These models were crucial for investigating hair disorders and developing potential treatments, with a focus on synthesizing information from different models to enhance understanding of hair follicle function in health and disease.
research A Review of Hair Anatomy and Animal Models for Alopecia
The paper concludes that animal models help in understanding hair loss causes and developing new treatments.
research Alopecia Areata: Animal Models
Alopecia areata is influenced by genetics and immune system factors, and better understanding could improve treatments.
research Sex Differences in Animal Models of Sodium Valproate-Induced Autism in Postnatal BALB/c Mice: Whole-Brain Histoarchitecture and 5-HT2A Receptor Biomarker Evidence
Male mice are more susceptible to autism-like changes from valproic acid than female mice.
research An Overview of Animal Models Induced by Glucocorticoids
Glucocorticoids can cause various health issues, but some treatments may help reduce these effects.
research Administration of Dutasteride in Animal Models of Retinitis Pigmentosa
Dutasteride potentially improves cell survival and reduces retinal damage in retinitis pigmentosa.
research Effect of 5-Alpha Reductase Inhibitors in Animal Models of Parkinson's Disease
5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.
research The 5α-Reductase Inhibitor Finasteride Reduces Opioid Self-Administration in Animal Models of Opioid Use Disorder
Finasteride reduces opioid use and withdrawal symptoms in animals.
research Review on Methods and Mechanisms for Producing Polycystic Ovary Syndrome (PCOS) in Animal Models: Experimental Purpose (Pre-Clinical Studies)
The document concludes that there are multiple ways to create PCOS in animals for research, which helps understand and treat the condition.
research Androgens’ Effects Across the Lifespan in Men and Animal Models
Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.
research Growth Factors and Cytokines in Hair Follicle Development and Cycling: Recent Insights from Animal Models and the Potentials for Clinical Therapy
Growth factors and cytokines are important for hair growth and could potentially treat hair loss, but more research is needed to overcome challenges before they can be used in treatments.
research Immune Cells in Cutaneous Wound Healing: A Review of Functional Data from Animal Models
Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.
research In Vivo and In Vitro Exposure to Free Fatty Acids Induce Increased Androgen Production in Animal Models: A Potential Pathogenic Factor of Polycystic Ovary Syndrome
Free fatty acids may increase androgen production, potentially contributing to polycystic ovary syndrome.
research Investigation of the Cognitive Activity Between the Leaf Extracts of Eclipta Alba and Ziziphus Jujuba in Diabetic Animal Models
Ziziphus jujuba and Eclipta alba leaf extracts improve blood sugar levels and cognitive function in diabetic rats.
research Finding Models for Skin Diseases: Successes and Failures
The document concludes that while finding animal models for the skin disease Hidradenitis suppurativa is challenging, certain mouse mutations may provide useful insights for research and drug testing.
research Androgenetic Alopecia: In Vivo Models
Stump-tailed macaque best for researching hair loss causes and treatments.
research In Vitro Models to Study Hair Follicle Generation
Scientists can now grow hair-like structures in a lab using special 3D culture systems, which could potentially help people with hair loss or severe burns.