TLDR The best animal model for studying male-pattern baldness is the stumptailed macaque, not rats or mice.
The document discussed the lack of a genetic model for androchronogenic alopecia in rats and mice, noting that the best current animal model is the stumptailed macaque, a primate whose hair loss pattern closely resembles human male-pattern baldness. It suggested that genetically controlled regional hairlessness might be unique to humans, making it unlikely to find a similar process in rodents.
7 citations
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October 1988 in “Clinics in Dermatology” Minoxidil can promote hair growth in hairless mice.
54 citations
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June 1985 in “American Journal of Dermatopathology” Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.
21 citations
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April 1982 in “Genetics Research” Mice with the naked gene have missing or abnormal hair cells.
40 citations
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February 1946 in “Canadian Journal of Research/Canadian journal of research” Hereditary factors cause hair loss in mice by affecting skin and hair follicle structure.
8 citations
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October 1988 in “Clinics in dermatology” The best animal model for studying male-pattern baldness is the stumptailed macaque, not rats or mice.
