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research The effect of testosterone, cyproterone acetate, and minoxidil on hair loss in the androchronogenetic alopecia mouse

12 citations , October 1988 in “Clinics in dermatology”

This report introduces a mouse model with androgen-dependent alopecia, suggesting it as a potential alternative for studying hair loss mechanisms and testing treatments.

research The extract of Thujae occidentalis semen inhibited 5α-reductase and androchronogenetic alopecia of B6CBAF1/j hybrid mouse

47 citations , April 2003 in “Journal of dermatological science”

This study showed that Thujae occidentalis semen extract inhibited 5alpha-reductase type 2 in laboratory tests and reduced androgen-related hair loss in animal models, suggesting potential use for male pattern baldness.

research Animal models of alopecia

8 citations , October 1988 in “Clinics in dermatology”

This paper discusses the lack of a genetic model for androchronogenic alopecia in rodents, noting the stumptailed macaque as a better current model due to its similarities to human male-pattern baldness; it reports no new results.

research Androgenetic Alopecia: In Vivo Models

27 citations , October 1999 in “Experimental and Molecular Pathology”

This article reviews potential animal models for studying androgenetic alopecia and reports no new experimental results; the authors highlight the need for further development of rodent models.

research Drug discovery for alopecia: gone today, hair tomorrow

70 citations , February 2015 in “Expert Opinion on Drug Discovery”

This review discusses current knowledge on the biological mechanisms of different types of alopecia but reports no new clinical findings; the authors highlight future research directions, especially regarding epidermal stem cells and immune pathways.

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learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Procyanidin

Are Procyanidin based hair tonics or shampoos effective against androgenic alopecia? Three small trials of topical procyanidin in 29 to 43 men, all run by the company that developed it, reported modest hair-count gains after four to six months. No independent trial has confirmed them, and procyanidin is not an approved treatment for pattern hair loss.

learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 has been studied only in men with androgenetic alopecia, in two Phase 1 studies and one 16-week Phase 2 trial. There is no research on it in women or in any other type of hair loss.
What is TDM-105795, and why is it being studied as a potential product for hair loss and hair growth support? TDM-105795 is an experimental topical drug that has been tested only in men with androgenetic alopecia, in two Phase 1 studies and one 16-week Phase 2 trial of 71 men. It is not approved, and no peer-reviewed trial results have been published.

learn Trichogen® (foligain)

learn Nanoxidil

learn Azelaic Acid

azelaic acid: Does it work for all types of hair loss or just DHT? One small randomised trial (26 women, no placebo) found no significant difference between 5% azelaic acid and 2% minoxidil for female pattern hair loss, which is too small to show they work equally well, and the anti-DHT rationale rests on laboratory work. For alopecia areata, telogen effluvium and seborrhoeic dermatitis there is no trial evidence for azelaic acid at all.

learn GT20029

Is GT20029 safe and effective for both men and women with androgenic alopecia? Not known yet. GT20029 is an experimental drug tested only in men: in one 12-week trial two of four regimens beat placebo with similar side-effect rates, and long-term safety and effects in women or pregnancy are unstudied.

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Community Join

5 / 1000+ results

community Evolution theory: AGA is your body trying to reduce the risk of prostate cancer by exposing your scalp to more UV

in Research/Science 9 months ago

Androgenic alopecia (AGA) might have evolved to reduce prostate cancer risk by increasing UV exposure to the scalp, but this theory is debated. Treatments like minoxidil and finasteride are used for AGA, though the exact causes and evolutionary reasons for hair loss are unclear.

community AGA/male pattern baldness and loss of hair in the past 6months

52 upvotes 8 months ago

A 25-year-old male experienced significant hair loss due to telogen effluvium and androgenetic alopecia. He began using finasteride, minoxidil, and vitamins, seeing some regrowth but remains worried about hair density.

community From Perfect Hair to This: 2 Years of Chronic TE + Unmasked AGA.

in Treatment 5 upvotes 5 months ago

A 25-year-old is experiencing chronic telogen effluvium (TE) and androgenetic alopecia (AGA) after surgery, using finasteride, red light therapy, and supplements, and considering oral minoxidil despite heart concerns. They are unsure whether to start minoxidil before or after an upcoming surgery, which may trigger another hair shed.

community Eliminate/Confirm AGA based on blood report

in General 126 upvotes 1 year ago

A 19-year-old male with no family history of androgenetic alopecia (AGA) is experiencing hair loss and considering using a topical minoxidil and finasteride mixture. Despite low vitamin D levels and normal DHT serum levels, he seeks confirmation of AGA before starting treatment.

community May have been mis-diagnosed for 10 years, self-investigation into AGA + AA Incognita (Defused Shedding)

1 upvotes 2 years ago

A 27-year-old male with AGA and diffused thinning has been using oral Minoxidil, Finasteride, Vitamin D, B12, Iron, and Ketoconazole shampoo. Despite a hair transplant and improved blood levels, he continues to experience hair loss and suspects a possible misdiagnosis of Alopecia Areata Incognita.

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