TLDR Animal experiments help understand and test treatments for healing wounds and reducing scars.
The document from January 1, 2016, discussed the use of both small and large animal models for the purpose of evaluating skin substitutes and the topical application of biological and chemical formulations, with a focus on their effects on wound healing and scarring. It also covered the criteria for selecting appropriate animal models and the development of models for both chronic and acute wounds. The chapter aimed to provide insights into the methodologies for studying wound healing processes and the efficacy of treatment options using animal subjects.
1279 citations
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November 2005 in “Nature Medicine” 168 citations
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January 2005 in “Journal of Investigative Dermatology” Male and female mice have different skin thickness, and hormones affect their skin and hair growth differently.
24 citations
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September 2020 in “Pharmaceutics” Lidocaine-loaded microparticles effectively relieve pain and fight bacteria in wounds.
Silk sericin dressing with collagen heals wounds faster and improves scar quality better than Bactigras.
133 citations
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July 2020 in “Cells” Creating fully functional artificial skin for chronic wounds is still very challenging.
122 citations
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December 2022 in “International Journal of Molecular Sciences” Nanoparticles improve skin treatment but need more research on safety and effectiveness.
25 citations
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November 2022 in “Frontiers in Bioengineering and Biotechnology” Composite biodegradable biomaterials can improve diabetic wound healing but need more development for clinical use.