Clinical Efficacy of Silk Sericin Dressing with Collagen for Split-Thickness Skin Graft Donor Site Treatment

The study evaluated the clinical efficacy of a silk sericin dressing with collagen (SDC) for split-thickness skin graft (STSG) donor sites, involving 21 patients with 30 donor sites. SDC significantly reduced wound healing time (15.00 ± 7.00 days) compared to Bactigras (16.00 ± 8.00 days, p=0.015) and improved scar quality, including lower melanin and erythema levels, better Vancouver Scar Scale (VSS) and Patient and Observer Scar Assessment Scale (POSAS) scores, and higher skin hydration. Pain scores, infection rates, and adverse effects were similar between the groups. The findings suggest that SDC is a viable alternative for STSG donor site treatment, promoting faster healing and better scar quality.