TLDR Scalp skin grafts effectively cover lower limb defects with high success and minimal complications.
The study at the University Clinic of Navarra investigated using ultra-thin split-thickness skin grafts (STSGs) from the scalp to cover lower extremity defects in 15 patients with conditions like venous ulcers and carcinomas. Grafts were harvested using a DermaBlade and showed a 90% success rate, with complete healing typically in 24 days and no significant complications. The scalp's rapid healing and minimal scarring made it an effective donor site, with no hair transfer or alopecic scarring observed. The method proved simple, fast, and reproducible, offering excellent cosmetic results and patient satisfaction, though further studies with larger sample sizes are recommended.
7 citations,
August 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” Scalp-to-scalp skin grafts quickly heal and hide well under regrown hair, making them good for repairing large scalp defects.
4 citations,
January 2022 in “Transfusion Medicine and Hemotherapy” Platelet-Rich Plasma (PRP) has potential benefits in plastic surgery, especially for skin grafts, wound healing, hair loss, mild Carpal Tunnel Syndrome, and TMJ disorders, but more research is needed to confirm its effectiveness.
56 citations,
March 2016 in “International Wound Journal” Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.
14 citations,
January 2021 in “Scientific Reports” Using micro skin tissue columns improves skin wound healing and reduces scarring.
43 citations,
July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
August 2023 in “International journal of medical science and clinical research studies” PRP therapy helps heal pediatric surgical wounds faster and with fewer scars but needs more research for safety and cost.
