Platelet-Rich Plasma in Plastic Surgery: A Systematic Review

    January 2022 in “ Transfusion Medicine and Hemotherapy ”
    Sophie Hasiba-Pappas, Alexandru Tuca, Hanna Luze, Sebastian P. Nischwitz, Robert Zrim, Judith C. J. Holzer-Geissler, David B. Lumenta, Lars-P. Kamolz, Raimund Winter
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    TLDR Platelet-Rich Plasma (PRP) has potential benefits in plastic surgery, especially for skin grafts, wound healing, hair loss, mild Carpal Tunnel Syndrome, and TMJ disorders, but more research is needed to confirm its effectiveness.
    The systematic review "Platelet-Rich Plasma in Plastic Surgery" evaluated 50 studies on the use of Platelet-Rich Plasma (PRP) in various applications in plastic surgery. The review found that PRP therapy showed several beneficial effects, but its efficacy was not universally proven due to variation in preparation protocols and treatment strategies. PRP showed significantly better results in skin grafting and wound treatment, and was found to be a safe and suitable alternative for managing hair loss, improving hair regrowth, density, and count. It was also effective in reducing symptom severity and improving hand function in mild Carpal Tunnel Syndrome (CTS) patients, and was more efficient than arthrocentesis in treating Temporomandibular Joint (TMJ) disorders. However, the review concluded that more extensive research and larger studies are needed to further evaluate the efficacy of PRP in various fields of plastic surgery.
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