The Role of the Skin Microbiome in Wound Healing

    January 2024 in “ Burns and trauma ”
    Yankun Yang, Jiuzuo Huang, Ang Zeng, Xiao Long, Nanze Yu, Xiaojun Wang
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    TLDR The skin microbiome helps heal wounds and can be targeted to improve healing.
    This review discusses the significant role of the skin microbiome in wound healing, emphasizing its dual role in maintaining skin barrier integrity and contributing to skin disorders, including problematic wound healing. It examines the microbiome composition in various wound types and outcomes using next-generation sequencing. The review also delves into the mechanisms of host-microbe and microbe-microbe interactions during the healing process and suggests potential therapeutic strategies targeting the skin microbiome to enhance healing outcomes.
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