The Skin Microbiome: Current Landscape and Future Opportunities

    February 2023 in “ International Journal of Molecular Sciences ”
    Paisleigh Smythe, Holly N. Wilkinson
    TLDR The skin microbiome is crucial for skin health, and more research is needed to explore its role and potential treatments.
    The review explores the critical role of the skin microbiome in maintaining skin health, highlighting its complexity and the need for further research to understand its interactions with the skin. It discusses the diversity of the skin's microbial communities, including bacteria, fungi, viruses, and archaea, and how factors like age, genetics, and environment influence microbial composition. The document emphasizes the impact of intrinsic and extrinsic aging on microbial diversity, with aged skin showing higher diversity and changes in dominant bacteria. It calls for advanced research techniques, such as next-generation sequencing, to better understand the microbiome's role in skin health and disease, and suggests potential therapeutic approaches, including probiotics and bacteria-derived treatments, to address microbial dysbiosis and skin conditions.
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