The Immunology of the Porcine Skin and Its Value as a Model for Human Skin
July 2015
in “
Molecular immunology
”
TLDR Porcine skin is very similar to human skin, making it a useful model for research.
The document reviewed the immunological properties of porcine skin, emphasizing its structural and compositional similarities to human skin, making it a valuable pre-clinical model for dermatological research. It focused on dendritic cells (DCs) in pig skin, proposing classifications for porcine DC subsets that corresponded to human DC subsets based on specific phenotypic markers. The review highlighted the pig's utility in studying skin immunology, wound healing, transdermal delivery, and other dermatological areas, and suggested future studies to confirm these findings through transcriptomic analysis.
