Immunological Challenges Associated With Artificial Skin Grafts: Available Solutions and Stem Cells in Future Design of Synthetic Skin

    December 2017 in “ Journal of Biological Engineering ”
    Saurabh Dixit, Dieudonné R. Baganizi, Rajnish Sahu … Vida A. Dennis
    Studysummary This review discusses the challenges of skin graft acceptance and examines current strategies and alternatives for full-thickness skin replacement and repair, noting that immunological rejection remains a significant hurdle.
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    Research cited in this study 8

    1. Bioengineering a 3D Integumentary Organ System from iPS Cells Using an In Vivo Transplantation Model Science Advances · 2016
    2. Advanced Therapies for Skin Injuries Wiener Klinische Wochenschrift · 2015
    3. Human Wharton’s Jelly Mesenchymal Stem Cells Plasticity Augments Scar-Free Skin Wound Healing with Hair Growth PloS one · 2014
    4. Mechanisms Regulating Skin Immunity and Inflammation Nature Reviews Immunology · 2014
    5. Ultraviolet Radiation in Wound Care: Sterilization and Stimulation Advances in wound care · 2013
    6. Human Induced Pluripotent Stem Cell-Derived Ectodermal Precursor Cells Contribute to Hair Follicle Morphogenesis In Vivo ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2013
    7. Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches Nature Communications · 2012
    8. The Role of Stem Cells in Cutaneous Wound Healing: What Do We Really Know? Plastic and Reconstructive Surgery · 2011

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