Animal Models of Psoriasis: What Can We Learn from Them?

    April 1999 in “ Journal of Investigative Dermatology ”
    Michael P. Schön
    Studysummary This review compares various rodent models that reflect aspects of psoriasis with human psoriasis and potential applications for research, reporting no new clinical findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 5

    1. Transgenic Mice Expressing IFN-γ in the Epidermis Have Eczema, Hair Hypopigmentation, and Hair Loss Journal of Investigative Dermatology · 1997
    2. A Polygenic Mouse Model of Psoriasiform Skin Disease in CD18-Deficient Mice Proceedings of the National Academy of Sciences · 1996
    3. Targeting Expression of Keratinocyte Growth Factor to Keratinocytes Elicits Striking Changes in Epithelial Differentiation in Transgenic Mice The EMBO Journal · 1993
    4. Interleukin 6: Insights Into Its Function in Skin by Overexpression in Transgenic Mice Proceedings of the National Academy of Sciences · 1992
    5. Transgenic Mice Provide New Insights Into the Role of TGF-Alpha During Epidermal Development and Differentiation Genes & Development · 1991