Cicatricial (Scarring) Alopecias: Comprehensive Review and Management

    Franco Rongioletti, Konstantina Christana
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    TLDR Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
    The 2012 document provides a comprehensive review of cicatricial (scarring) alopecias, which are hair loss disorders resulting in the destruction of hair follicles and their replacement with scar tissue. It emphasizes the complexity of diagnosing these conditions, which often requires a combination of clinical assessment, dermatoscopy, and histopathological studies. The document discusses various hypotheses for the pathogenesis of these disorders, including autoimmune mechanisms and genetic factors, and outlines the North American Hair Research Society's classification system. It also describes the clinical features and management of specific cicatricial alopecias, such as Folliculitis Decalvans and Dissecting Cellulitis, as well as treatment options for conditions like discoid lupus erythematosus (DLE) and lichen planopilaris (LPP). The document highlights the lack of randomized controlled trials for treatment at the time and the need for early intervention to prevent further hair loss. It also notes the challenges in treatment, which aim to slow or stop disease progression, and the potential use of surgical options in certain cases.
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