Cicatricial (Scarring) Alopecias: Comprehensive Review and Management

    Franco Rongioletti, Konstantina Christana
    Image of study
    TLDR Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.
    The 2012 document provides a comprehensive review of cicatricial (scarring) alopecias, which are hair loss disorders resulting in the destruction of hair follicles and their replacement with scar tissue. It emphasizes the complexity of diagnosing these conditions, which often requires a combination of clinical assessment, dermatoscopy, and histopathological studies. The document discusses various hypotheses for the pathogenesis of these disorders, including autoimmune mechanisms and genetic factors, and outlines the North American Hair Research Society's classification system. It also describes the clinical features and management of specific cicatricial alopecias, such as Folliculitis Decalvans and Dissecting Cellulitis, as well as treatment options for conditions like discoid lupus erythematosus (DLE) and lichen planopilaris (LPP). The document highlights the lack of randomized controlled trials for treatment at the time and the need for early intervention to prevent further hair loss. It also notes the challenges in treatment, which aim to slow or stop disease progression, and the potential use of surgical options in certain cases.
    Discuss this study in the Community →

    Research cited in this study

    28 / 28 results

    Related Community Posts Join

    6 / 13 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Comprehensive Microneedling Guide

      in Microneedling  295 upvotes 2 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Exploring Bryan Johnson's Hair Routine In Detail

      in Research/Science  65 upvotes 10 months ago
      Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.

    Related Research

    8 / 8 results