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    GlossaryAutoimmune Mechanisms

    body's immune system mistakenly attacks its own tissues

    Autoimmune mechanisms refer to the processes by which the body's immune system mistakenly attacks its own tissues, thinking they are foreign invaders. This can lead to various autoimmune diseases, such as alopecia areata, where the immune system targets hair follicles, resulting in hair loss. Understanding these mechanisms is crucial for developing treatments that can modulate the immune response and prevent tissue damage.

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      community 27/M closing in on a year of fin and min, feel like it’s only gotten worse.

      in Chat  62 upvotes 1 year ago
      A user reported no improvement in hair loss after nearly a year of using 1mg oral finasteride, topical minoxidil twice daily, and weekly microneedling. Other users suggested the possibility of DUPA or retrograde alopecia and mentioned that treatments might only slow down hair loss rather than regrow hair.

      community Not everyone should immediately go on Fin if they are starting to bald

      in Finasteride/Dutasteride  21 upvotes 2 years ago
      The conversation suggests that people should consult a dermatologist to understand their type of hair loss before starting treatments like finasteride or dutasteride, especially if they have autoimmune issues or low DHT. Some participants believe in starting treatment like finasteride immediately if hair loss is due to DHT, while others recommend ruling out other causes and considering minoxidil first, especially for younger individuals.

      community Reminder how little the average person knows about hair loss

      in Satire  642 upvotes 3 years ago
      How little the average person knows about hair loss and how it can be an unfairly stigmatized issue, even by people with little knowledge of it themselves. Some specific treatments that were discussed include finasteride, RU58841, dutasteride, minoxidil, pyritinol, dermarolling, and diet/lifestyle changes.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      by nkrata in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.