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natural substance from Neem tree with medicinal and pesticidal properties
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signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
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extract, clone, and reinsert your own hair cells
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research An Appraisal of Laboratory Models of Androgenetic Alopecia: A Systematic Review
Better hair loss models needed for research.
research Modeling Animal Genomics in Mice: An Authentic Approach for the Functional Interrogation of Evolutionarily and Agriculturally Critical Variants
Mouse models are essential for studying and improving genetic traits in agriculture.
research Bioengineered Skin Organoids: From Development to Applications
Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
research Drug Discovery for Alopecia: Gone Today, Hair Tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
research Low-Level Laser Treatment Promotes Skin Wound Healing by Activating Hair Follicle Stem Cells in Female Mice
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5 / 90 resultscommunity A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.
Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.
community HairClone developing cell replacement treatments for Hair Loss
HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.
community The story of RU58841/ PSK3841
by
Typical-Promise-3001
in Research
622 upvotes
1 year ago RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.
community FCE 28260: A Forgotten 5α-Reductase Inhibitor
by
nkrata
in Research
330 upvotes
1 year ago FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community Accelerated Hair Loss from Creatine
Creatine may cause hair loss in some individuals, especially those on finasteride, despite no scientific link. Personal experiences suggest individual sensitivity to DHT could be a factor.