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    GlossaryAnimal Models (in vivo models)

    non-human animals used to study biological processes and diseases

    Animal models are non-human animals used in scientific research to study biological processes and diseases, including conditions like alopecia. These models help researchers understand how diseases develop and progress, and they are crucial for testing the safety and effectiveness of new treatments before they are used in humans.

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      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn Caffeine

      the stimulant you know and love can be used topically to stimulate hair

      learn KY19382

      compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

      learn Procyanidin

      bioflavonoid found in plants with antioxidant and hair stimulating properties

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      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  42 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Connection between finasteride and nafld?

      in Research/Science  4 upvotes 2 months ago
      Finasteride may affect liver function and cortisol levels, potentially linking it to non-alcoholic fatty liver disease (NAFLD). More research is needed to understand this connection fully.

      community Surprisingly thorough study on He-Shou-Wu/Fo Ti

      in Research/Science  14 upvotes 1 year ago
      He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  735 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.