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Glossary Laboratory Mice

specially bred mice used for scientific research and experiments

Laboratory mice, also known as lab mice or research mice, are specially bred mice used in scientific research to study genetics, diseases, and the effects of various treatments. They are valuable because of their genetic similarity to humans, their short reproductive cycles, and the ability to control their environment and genetics, making them ideal for controlled experiments.

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Research

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Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: An Update

research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update

52 citations , October 2012 in “Journal of Dermatological Science”

This review presents updated tables of mouse mutants with hair growth abnormalities to aid in understanding the molecular mechanisms of human hair disorders, but reports no new clinical results.

Mutant Laboratory Mice With Abnormalities in Hair Follicle Morphogenesis, Cycling, and Structure: Annotated Tables

research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: annotated tables

86 citations , December 2001 in “Experimental dermatology”

This review classifies mutant mice with hair abnormalities into six categories, providing an annotated table that serves as a reference for understanding the molecular controls of hair growth.

research Genetically modified laboratory mice with sebaceous glands abnormalities

22 citations , July 2016 in “Cellular and Molecular Life Sciences”

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

research Analysis of Hair Follicles in Mutant Laboratory Mice

38 citations , November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

This article reviews the anatomical complexity and developmental aspects of hair follicles for analyzing abnormalities, but reports no new clinical findings.

research Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice

22 citations , May 2021 in “Nature Communications”

This study found that in wound-induced hair neogenesis, African spiny mice and laboratory mice exhibit different morphogenetic field formation patterns related to tissue stiffness, suggesting evolutionary developmental biology advantages.

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Community Join

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community Hair Multiplication Projects in China - Promising clinical trial results on Mice

34 upvotes 1 year ago

A breakthrough in hair follicle cultivation using induced pluripotent stem cells (iPSCs) has been achieved, producing large hair follicles suitable for transplantation. Clinical trials for this hair multiplication technology are planned in partnership with Yinguan Biotechnology.

community OrganTech Aims to Regenerate Hair and Teeth, trial on Mice show positive results

86 upvotes 1 year ago

OrganTech is working on regenerating hair and teeth, with positive results in mice, but skepticism remains about progress for humans. Users express frustration over the lack of advancements in human hair loss treatments, despite ongoing research and trials.

community Got my Oleic fatty acid they used in Korean study. Fuck you mice!

247 upvotes 8 months ago

Oleic acid and microneedling are being explored for hair regrowth, but results are mixed. Addressing DHT and fibrosis is crucial, with treatments like finasteride, minoxidil, and scalp massage also discussed.

community Stimulating existing stem cells to grow hair.

121 upvotes 3 years ago

Hair regrowth treatments, including stem cell injections, are discussed, with skepticism about their effectiveness compared to Minoxidil and finasteride. Derma stamping is mentioned as effective when used with Minoxidil, finasteride, and dutasteride.

community Is this true? It can be a major breakthrough

1008 upvotes 5 months ago

Deoxyribose sugar gel may stimulate hair regrowth similarly to minoxidil by enhancing blood supply and follicle activity. Human trials are necessary, and current products have mixed results.

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Learn

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learn SCUBE3

How does SCUBE3 work on hair follicles compared to treatments like minoxidil or finasteride? Laboratory research in mice reports that SCUBE3, a protein released by dermal papilla cells, signals dormant follicles to grow through the TGF-β pathway downstream of Hedgehog; minoxidil and finasteride instead work on blood flow to the follicle and on DHT, and unlike SCUBE3 they have decades of human trial data behind them. SCUBE3 has not been tested in human clinical trials and is not available as a medicine.

learn Ecklonia Cava

Is Ecklonia Cava better taken orally or applied topically for thinning hair? There is no human trial of Ecklonia cava for hair loss by either route, so neither oral nor topical use is established; the published work is laboratory studies on human cells and topical studies in mice.

learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Clinics

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