Signaling Involved in Hair Follicle Morphogenesis and Development
January 2014
in “
International Journal of Molecular Sciences
”
hair follicle morphogenesis Wnt signaling Shh signaling Notch signaling BMP signaling epithelial cancers crosstalk epithelial cells mesenchymal cells primary cilia estrogen hair cycle phases HF stem cell quiescence HF differentiation HF maintenance signaling pathway mutations alopecia stem cell-based therapies carcinogenesis hair follicle development Wnt Sonic Hedgehog Bone Morphogenetic Protein hair loss stem cell treatments cancer
Studysummary This article reviews the complex signaling pathways between epithelial and mesenchymal cells crucial for hair follicle morphogenesis, highlighting the Wnt pathway's role as a master regulator without reporting new experimental findings.
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