Sebaceous Gland Organoid Engineering

    January 2024 in “ Burns & Trauma ”
    Yiqiong Liu, Huanhuan Gao, Chen Hua-ting … Xiaoyan Sun
    Studysummary This review discusses recent advancements in engineering sebaceous gland organoids for potential regenerative applications, highlighting strategies to create functionalized organoids but reports no new clinical results.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 23

    1. Generation And Characterization Of Hair-Bearing Skin Organoids From Human Pluripotent Stem Cells Nature Protocols · 2022
    2. Hair-Bearing Human Skin Generated Entirely From Pluripotent Stem Cells Nature · 2020
    3. Blimp1+ Cells Generate Functional Mouse Sebaceous Gland Organoids In Vitro Nature communications · 2019
    4. Homeostasis of the Sebaceous Gland and Mechanisms of Acne Pathogenesis British Journal of Dermatology · 2019
    5. Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium Cell · 2019
    6. JunB Defines Functional And Structural Integrity Of The Epidermal-Pilosebaceous Unit In The Skin Nature Communications · 2018
    7. Loss of Gata6 Causes Dilation of the Hair Follicle Canal and Sebaceous Duct Experimental Dermatology · 2018
    8. Hair Growth Cycle Is Arrested in SCD1 Deficiency by Impaired Wnt3a-Palmitoleoylation and Retrieved by the Artificial Lipid Barrier Journal of Investigative Dermatology · 2017
    9. Genetically Modified Laboratory Mice with Sebaceous Glands Abnormalities Cellular and Molecular Life Sciences · 2016
    10. Sebaceous Lipids Are Essential for Water Repulsion, Protection Against UVB-Induced Apoptosis, and Ocular Integrity in Mice Development · 2016
    11. Deciphering the Functions of the Hair Follicle Infundibulum in Skin Physiology and Disease Cell and Tissue Research · 2014
    12. Generation of Folliculogenic Human Epithelial Stem Cells from Induced Pluripotent Stem Cells Nature communications · 2014
    13. Ligand-Independent Epidermal Growth Factor Receptor Hyperactivation Increases Sebaceous Gland Size and Sebum Secretion in Mice Experimental Dermatology · 2013
    14. C-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis Cell reports · 2013
    15. Wnt Signaling in Skin Development, Homeostasis, and Disease Cold Spring Harbor Perspectives in Biology · 2012
    16. TCF/Lef1 Activity Controls Establishment of Diverse Stem and Progenitor Cell Compartments in Mouse Epidermis The EMBO Journal · 2011
    17. Sebum Free Fatty Acids Enhance the Innate Immune Defense of Human Sebocytes by Upregulating Beta-Defensin-2 Expression Journal of Investigative Dermatology · 2009
    18. Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis Cell stem cell · 2009
    19. Hedgehog Signaling, Keratin 6 Induction, And Sebaceous Gland Morphogenesis American Journal Of Pathology · 2008
    20. The Role of Fibroblast Growth Factor Receptor 2b in Skin Homeostasis and Cancer Development The EMBO Journal · 2007
    21. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    22. Tcf3 and Lef1 Regulate Lineage Differentiation of Multipotent Stem Cells in Skin Genes & Development · 2001
    23. The Formation of Vellus Hair Follicles from Human Adult Epidermis Journal of Investigative Dermatology · 1956