Hair Growth Cycle Is Arrested in SCD1 Deficiency by Impaired Wnt3a-Palmitoleoylation and Retrieved by the Artificial Lipid Barrier
March 2017
in “
Journal of Investigative Dermatology
”
Research cited in this study
11 / 11 results
research Emerging Interactions Between Skin Stem Cells and Their Niches
Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
research Wnt Signaling in Skin Development, Homeostasis, and Disease
Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.
research TCF/Lef1-Mediated Control of Lipid Metabolism Regulates Skin Barrier Function
TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.
research Obesity Resistance of the Stearoyl-CoA Desaturase-Deficient (Scd1 -/-) Mouse Results from Disruption of the Epidermal Lipid Barrier and Adaptive Thermoregulation
Deleting the scd1 gene in mice prevents obesity by disrupting skin lipids and improving heat regulation.
research Defining the Impact of Beta-Catenin/Tcf Transactivation on Epithelial Stem Cells
β-catenin is essential for stem cell activation and proliferation in hair follicles.
research Molecular Principles of Hair Follicle Induction and Morphogenesis
Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
research Transient Activation of Beta-Catenin Signaling in Adult Mouse Epidermis Induces New Hair Follicles, Continuous Activation Maintains Tumors
Temporary activation of β-catenin can create new hair follicles, but ongoing activation is needed to keep hair follicle tumors.
research Manipulation of Stem Cell Proliferation and Lineage Commitment: Visualization of Label-Retaining Cells in Wholemounts of Mouse Epidermis
Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.
research Asebia-2J (Scd1ab2J): A New Allele and a Model for Scarring Alopecia
The absence of functional sebaceous glands causes hair follicle destruction and scarring alopecia.
research Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation
Activated LEF/TCF complexes are crucial for hair development and cycling.
research Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages During Skin Development
Keratin 17 is important for skin development and may help define skin cell types.
Related Research
5 / 5 results
research Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles
Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.
research Expression of Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinases in the Hair Cycle
MMP-2 and MMP-9 help hair grow, while their inhibitors peak when hair growth slows.
research Dermal Papilla-Derived Wnt Ligands Are Required for Adult Hair Follicle Growth
Wnt ligands, produced by dermal papilla cells, are essential for adult hair growth and regeneration.
research Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling
FGF18 helps keep hair in its resting phase, affecting hair growth cycles.
research Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle
Vitamin D receptors in hair follicles change with the hair cycle, affecting hair growth.