142 citations
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September 2020 in “Journal of neurophysiology” This study estimates that young adults have about 230,000 tactile afferent fibers innervating their skin, with density varying by region and decreasing with age.
43 citations
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November 1988 in “The Journal of Comparative Neurology” This study examined the sensory innervation of hair follicles in the furry skin of rat hindlimbs, finding significant differences among hair types in their innervation patterns and densities.
4 citations
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April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study estimates that approximately 230,000 tactile afferent fibers innervate the human body's skin, with varying densities across different regions correlating with spatial acuity and hair follicle density.
2 citations
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June 2025 in “International Journal of Nanomedicine” This review examines emerging biomaterial strategies designed to support both neural regeneration and cutaneous wound healing, emphasizing their potential to improve sensory function through mechanisms like axonal regrowth and vascular network formation, while noting the need for standardized assessments and clinically translatable designs.
This study found that the transcription factor Meis2 is crucial for the maturation and innervation of sensory neurons responsible for light touch in mice, with its absence leading to reduced touch sensitivity.