Transcriptomics Sequencing Reveals Qu-Shi-Yu-Fa Decoction Promotes Hair Cycle And Keratinization By Upregulating FOXN1 And TGM3 To Treat Androgenetic Alopecia

    May 2025 in “ Phytomedicine
    Mingxi Zhu, Yuan Fang, Ying Huang, W. QIU, Ling Ning, Yanan Li, Chengwei Zhu, Xiaoyu Song, Yuanyuan Wu, Wei Zou, Aiyun Wang, Lu Yin
    TLDR Qu-shi-yu-fa Decoction may help treat hair loss by promoting hair growth and strengthening.
    The study reveals that Qu-shi-yu-fa Decoction (QSYF), a traditional Chinese medicine formula, promotes hair cycle regulation and keratinization by upregulating the expression of FOXN1 and TGM3, providing therapeutic effects on androgenetic alopecia (AGA). This research offers new insights into the multi-target and multi-pathway mechanisms of Chinese medicine therapy for AGA, suggesting QSYF as a potential treatment option. The study emphasizes the need for alternative treatments due to the limited efficacy and side effects of current FDA-approved medications for AGA.
    Discuss this study in the Community →

    Research cited in this study

    22 / 22 results

    Related Community Posts Join

    6 / 8 results

      community Kintor long term safety phase 3

      in Research/Science  64 upvotes 1 month ago
      Kintor's phase III trial for pyri (KX-826) showed promising safety and efficacy results, with no drug-related sexual dysfunction reported. Users discussed their experiences with pyri, Minoxidil, Dutasteride, and concerns about the validity of the study results.

      community I’m Feeling so discouraged and depressed - No one wants to prescribe finasteride to me.

      in Finasteride/Dutasteride  68 upvotes 1 year ago
      A user in France is frustrated because three dermatologists refused to prescribe finasteride for their hair loss, suggesting it's not androgenetic alopecia (AGA) and offering expensive vitamin treatments instead. Other users suggest buying hair loss treatments like minoxidil and finasteride from various online pharmacies and considering a gender-affirming care physician for more understanding treatment options.

      community Tom Cruise at the Mission Impossible premiere hair.(He's 61 y/o)

      in Chat  392 upvotes 1 year ago
      The conversation speculates on whether Tom Cruise uses hair loss treatments like Finasteride or Dutasteride, with some suggesting he naturally has good hair like Brad Pitt, while others joke about Scientology or genetics playing a role. Specific treatments mentioned include Finasteride, Dutasteride, and possibly high-quality hair products or procedures like PRP (Platelet-Rich Plasma).

    Related Research

    3 / 3 results