Justicia Procumbens Prevents Hair Loss in Androgenic Alopecia Mice

    December 2023
    Dae‐Dong Kim, Eun-Young Lee, Pyeong Geun Choi … Chang Hwa Jung
    Studysummary This study found that an extract from Justicia procumbens may prevent hair loss in a mouse model of androgenic alopecia by enhancing hair follicle cell proliferation and improving hair characteristics.
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    Research cited in this study 24

    1. Age-Associated Thin Hair Displays Molecular, Structural, and Mechanical Characteristic Changes Journal of structural biology · 2022
    2. Comparison of Oral Minoxidil, Finasteride, and Dutasteride for Treating Androgenetic Alopecia Journal of Dermatological Treatment · 2022
    3. Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles Frontiers in Cell and Developmental Biology · 2022
    4. The Psychological Consequences of Androgenetic Alopecia: A Systematic Review Journal of Cosmetic Dermatology · 2022
    5. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    6. Hair Growth Stimulation Effect of Centipeda Minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways Biomolecules · 2021
    7. Recreation of a Hair Follicle Regenerative Microenvironment: Successes and Pitfalls Bioengineering & translational medicine · 2021
    8. Mesenchymal Stem Cells Antagonize IFN-Induced Proinflammatory Changes and Growth Inhibition Effects via Wnt/β-Catenin and JAK/STAT Pathway in Human Outer Root Sheath Cells and Hair Follicles International journal of molecular sciences · 2021
    9. Observation of the Expression of Vascular Endothelial Growth Factor and the Potential Effect of Promoting Hair Growth Treated with Chinese Herbal BeauTop Evidence-based Complementary and Alternative Medicine · 2021
    10. An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities Frontiers in Cell and Developmental Biology · 2020
    11. Hormonal Regulation in Male Androgenetic Alopecia: Sex Hormones and Beyond - Evidence from Recent Genetic Studies Experimental Dermatology · 2020
    12. Beta-Catenin-Mediated Hair Growth Induction Effect of 3,4,5-Tri-O-Caffeoylquinic Acid Aging · 2019
    13. Finasteride and Androgenic Alopecia: From Therapeutic Options to Medical Implications Journal of Dermatological Treatment · 2019
    14. Norgalanthamine Stimulates Proliferation of Dermal Papilla Cells via Anagen-Activating Signaling Pathways Biological & Pharmaceutical Bulletin · 2018
    15. Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling Cellular physiology and biochemistry · 2016
    16. The Impact of Oxidative Stress on Hair International Journal of Cosmetic Science · 2015
    17. Female Pattern Hair Loss: A Clinical and Pathophysiological Review Anais Brasileiros De Dermatologia · 2015
    18. The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells Journal of Investigative Dermatology · 2015
    19. The Human Hair: From Anatomy to Physiology International Journal of Dermatology · 2013
    20. Preventive Effects of Monascus on Androgen-Related Diseases: Androgenetic Alopecia, Benign Prostatic Hyperplasia, and Prostate Cancer Journal of Agricultural and Food Chemistry · 2013
    21. Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect Journal of Dermatological Science · 2011
    22. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010
    23. The Extract of Thuja Occidentalis Semen Inhibited 5α-Reductase and Androgenetic Alopecia in B6CBAF1/J Hybrid Mice Journal of dermatological science · 2003
    24. Androgenetic Alopecia: Pathogenesis and Potential for Therapy Expert Reviews in Molecular Medicine · 2002

    Related research 6

    1. Activation of Beta-Catenin Signaling in CD133-Positive Dermal Papilla Cells Drives Postnatal Hair Growth PLOS ONE · 2016
    2. Dermal Papilla-Derived Wnt Ligands Are Required for Adult Hair Follicle Growth Journal of Investigative Dermatology · 2016
    3. Dermal Sheath Cells Contribute to Postnatal Hair Follicle Growth and Cycling Journal of Dermatological Science · 2016
    4. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014
    5. Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle British Journal of Dermatology · 2006
    6. An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation Proceedings of the National Academy of Sciences of the United States of America · 1996