Exogenous Stimulations Change Nude Mouse Hair Cycle Pattern

The study investigated the impact of exogenous stimulations on the hair growth pattern of nude mice, revealing that hair growth occurred in waves from the head to the posterior back. Male nude mice exhibited a more regular hair cycle pattern than females. Exogenous stimulations significantly extended the hair-existing phase and reduced the no-hair phase without altering the overall hair growth pattern. Topical minoxidil was most effective in males, while in females, wounds were more effective than minoxidil in prolonging the hair-existing phase, though the effect was not pronounced.