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      learn GT20029

      research compound made to degrade androgen receptors in scalp

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      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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      community Pyrilutamide phase III clinical trial results released

      in Research/Science  31 upvotes 1 year ago
      Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

      community Pelage Announces Positive Results of Phase 2a Trials for PP405

      in Update  297 upvotes 4 months ago
      PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  126 upvotes 1 year ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.