Effects of Mixed Medicinal Herbal Extract on Hair Growth in Mice with Alopecia

January 2014

황미열, 도은주, 정금희, 김미려

medicinal herbal extract CS-10-H minoxidil alopecia hair growth C57BL/6 mice hair density hair thickness IGF-1 VEGF Rogaine

TLDR The herbal extract CS-10-H significantly promotes hair growth in mice.

The study investigated the effects of a mixed medicinal herbal extract (CS-10-H) on hair growth in C57BL/6 mice with alopecia. Male mice were treated with CS-10-H, 5% minoxidil, or a vehicle solution for 3 weeks. Both CS-10-H and minoxidil significantly stimulated hair growth compared to the vehicle, with hair density increasing by approximately 206% and 208%, and hair thickness by 220% and 200%, respectively, by day 14. Additionally, protein expression levels of hair growth factors IGF-1 and VEGF were significantly higher in the CS-10-H and minoxidil groups. The results suggested that CS-10-H could be a promising ingredient for hair growth products.

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