Applications and Efficacy of Minoxidil in Dermatology

    November 2024 in “ Skin Health and Disease
    Ramadan Hussein, Salman Bin Dayel, Othman Abahussein, Abeer A. El-Sherbiny
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    TLDR Minoxidil is effective for promoting hair growth and has various dermatological uses.
    Minoxidil, originally an antihypertensive, is now a key treatment for hair growth, particularly in androgenetic alopecia (AGA). It works by opening potassium channels and enhancing blood flow to hair follicles. The study reviews its effectiveness in various hair disorders, including alopecia areata and scarring alopecia, and explores new uses in dermatology, such as scar treatment and wound healing. Combination therapies with minoxidil, like finasteride and microneedling, show superior results in hair regrowth, with studies involving up to 93 participants. Common side effects include scalp irritation and hypertrichosis, especially with 5% solutions. The document emphasizes patient education and monitoring to improve adherence and suggests future research to explore new applications and improve treatment protocols.
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