Acne Scar Management: Minoxidil as a Promising Approach or a Mirage?
September 2023
in “
International journal of biomedicine
”
New to Minoxidil? There is a guide in the encyclopedia. Read the guide → 
Studysummary This review evaluated current evidence on minoxidil's potential to treat scars and reported reduced collagen accumulation and fibrosis in various studies, suggesting its antifibrotic effects may benefit wound healing; however, direct studies on acne scars are yet to be conducted.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
Minoxidil, commonly used for hypertension and hair loss, is being explored for its potential in treating atrophic and hypertrophic scars, such as those from acne. The review highlights minoxidil's antifibrotic properties, which include reducing collagen accumulation and fibrosis by inhibiting lysyl hydroxylases (LHs). These enzymes are crucial for collagen stability. Although direct studies on minoxidil's efficacy for acne scars are lacking, its inhibitory effects on fibroblast proliferation and migration in vitro and some in vivo studies suggest it could be a promising treatment for scar management.
