Medicinal and Edible Plant Allium Macrostemon Bunge for the Treatment of Testosterone-Induced Androgenetic Alopecia in Mice

    May 2023 in “ Journal of Ethnopharmacology ”
    Ruiyang Gao, Zhilun Yu, Cheng Lv … Wei Dou
    Studysummary In this study, Allium macrostemon Bunge extract was found to promote hair regrowth in a testosterone-induced androgenetic alopecia mouse model by activating Wnt/β-catenin signaling and boosting hair dermal papilla cell proliferation and growth factor expression.
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    Research cited in this study 28

    1. Activation of Camp Signaling in Response to Alpha-Phellandrene Promotes Vascular Endothelial Growth Factor Levels and Proliferation in Human Dermal Papilla Cells International journal of molecular sciences · 2022
    2. Tectoridin Stimulates the Activity of Human Dermal Papilla Cells and Promotes Hair Shaft Elongation in Mouse Vibrissae Hair Follicle Culture Molecules · 2022
    3. Dexpanthenol Promotes Cell Growth by Preventing Cell Senescence and Apoptosis in Cultured Human Hair Follicle Cells Current Issues in Molecular Biology · 2021
    4. Morus Alba Root Extract Induces the Anagen Phase in Human Hair Follicle Dermal Papilla Cells Pharmaceutics · 2021
    5. Hair Growth Stimulation Effect of Centipeda Minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways Biomolecules · 2021
    6. Application of Ethanol Extracts From Alnus Sibirica Fisch. ex Turcz in Hair Growth Promotion Frontiers in Bioengineering and Biotechnology · 2021
    7. Activation of Hair Cell Growth Factors by Linoleic Acid in Malva Verticillata Seed Molecules/Molecules online/Molecules annual · 2021
    8. KY19382, A Novel Activator of Wnt/β-Catenin Signalling, Promotes Hair Regrowth and Hair Follicle Neogenesis British Journal of Pharmacology · 2021
    9. Dihydrotestosterone-Induced Hair Regrowth Inhibition by Activating Androgen Receptor in C57BL6 Mice Simulates Androgenetic Alopecia Biomedicine & Pharmacotherapy · 2021
    10. Rescuing Key Native Traits in Cultured Dermal Papilla Cells for Human Hair Regeneration Journal of Advanced Research · 2020
    11. Oral Minoxidil Treatment for Hair Loss: A Review of Efficacy and Safety Journal of The American Academy of Dermatology · 2020
    12. Hair Growth Potential of Salvia Plebeia Extract and Its Associated Mechanisms Pharmaceutical Biology · 2020
    13. Hair Growth Promoting Effect of Houttuynia Cordata Extract in Cultured Human Hair Follicle Dermal Papilla Cells Biological & Pharmaceutical Bulletin · 2019
    14. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019
    15. Activating Wnt/β-Catenin Signaling Pathway for Disease Therapy: Challenges and Opportunities Pharmacology & Therapeutics · 2018
    16. Hair-Growth Potential of Ginseng and Its Major Metabolites: A Review on Its Molecular Mechanisms International Journal of Molecular Sciences · 2018
    17. Olfactory Receptor OR2AT4 Regulates Human Hair Growth Nature Communications · 2018
    18. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    19. Androgenetic Alopecia: A Review Endocrine · 2017
    20. Androgenetic Alopecia: An Update Of Treatment Options Drugs · 2016
    21. Malva Verticillata Seed Extracts Upregulate the Wnt Pathway in Human Dermal Papilla Cells International Journal of Cosmetic Science · 2015
    22. Exogenous IGF-1 Promotes Hair Growth by Stimulating Cell Proliferation and Downregulating TGF-β1 in C57BL/6 Mice In Vivo Growth Hormone & IGF Research · 2014
    23. The Inductive Effect of Ginsenoside F2 on Hair Growth by Altering the WNT Signal Pathway in Telogen Mouse Skin European Journal of Pharmacology · 2014
    24. Hair Growth-Promoting Effect of Aconiti Ciliare Tuber Extract Mediated by the Activation of Wnt/β-Catenin Signaling Life Sciences · 2012
    25. Promotion of Hair Growth by Rosmarinus Officinalis Leaf Extract Phytotherapy Research · 2012
    26. Beta-Catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair Developmental Cell · 2010
    27. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004
    28. Analysis of Apoptotic Cell Death in Human Hair Follicles In Vivo and In Vitro Journal of Investigative Dermatology · 1998