Development and Validation of a C57BL/6 Mouse Model of Androgenetic Alopecia Through Testosterone Propionate Induction
March 2026
in “
Trends in Sciences
”
Studysummary This study developed a testosterone propionate-induced C57BL/6 mouse model of androgenetic alopecia, demonstrating that high-dose, prolonged testosterone administration inhibited hair regrowth and mirrored human AGA pathology, providing a useful platform for studying hair loss mechanisms and testing therapies targeting the Wnt/β-catenin pathway.
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