Application of Ethanol Extracts From Alnus Sibirica Fisch. ex Turcz in Hair Growth Promotion
June 2021
in “
Frontiers in Bioengineering and Biotechnology
”
ethanol extracts Alnus sibirica oregonin hair follicle dermal papilla cells hair growth-related genes anti-oxidative anti-apoptotic hydrogen peroxide-induced cytotoxicity oxidative stress-induced cytokine testosterone-induced dihydrotestosterone production Insulin-like Growth Factor 1 IGF-1 Transforming Growth Factor Beta 1 TGF-β1 DHT hair loss hair follicle cells hair growth genes antioxidant hydrogen peroxide damage oxidative stress cytokine testosterone-induced DHT
Studysummary This study investigated the effects of the 60% alcohol extract from Alnus sibirica and its active compound, oregonin, on hair health, observing anti-oxidative and anti-apoptotic benefits in human hair dermal papilla cells exposed to oxidative stress, suggesting potential as natural materials for hair loss prevention.
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