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    Building Epithelial Tissues From Skin Stem Cells

    January 2008 in “ Cold Spring Harbor Symposia on Quantitative Biology ”
    Elaine Fuchs, Jonathan A. Nowak
    Studysummary This article reviews recent advancements in understanding skin stem cells and their roles in maintaining epidermal homeostasis and repairing wounds, without presenting new experimental findings.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 29

    1. Nfatc1 Balances Quiescence and Proliferation of Skin Stem Cells Cell · 2008
    2. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007
    3. Scratching the Surface of Skin Development Nature · 2007
    4. Genetic Basis of Skin Appendage Development Seminars in cell & developmental biology · 2007
    5. Bone Morphogenetic Protein Signaling Regulates the Size of Hair Follicles and Modulates the Expression of Cell Cycle-Associated Genes Proceedings of the National Academy of Sciences of the United States of America · 2006
    6. Bone Morphogenetic Protein Signaling Inhibits Hair Follicle Anagen Induction by Restricting Epithelial Stem/Progenitor Cell Activation and Expansion Stem Cells · 2006
    7. Rac1 Is Crucial for Hair Follicle Integrity but Not Essential for Epidermis Maintenance Molecular and Cellular Biology · 2006
    8. The Hair Cycle Journal of Cell Science · 2006
    9. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    10. Long-Term Renewal of Hair Follicles from Clonogenic Multipotent Stem Cells Proceedings of the National Academy of Sciences of the United States of America · 2005
    11. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005
    12. Defining the Impact of Beta-Catenin/Tcf Transactivation on Epithelial Stem Cells Genes & development · 2005
    13. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    14. Functions of Peroxisome Proliferator-Activated Receptors in Skin Homeostasis Lipids · 2004
    15. Transient Activation of Beta-Catenin Signaling in Adult Mouse Epidermis Induces New Hair Follicles, Continuous Activation Maintains Tumors Development · 2004
    16. Defining BMP Functions in the Hair Follicle by Conditional Ablation of BMP Receptor IA The Journal of Cell Biology · 2003
    17. Evidence That Myc Activation Depletes the Epidermal Stem Cell Compartment by Modulating Adhesive Interactions with the Local Microenvironment Development · 2003
    18. Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34 Journal of Investigative Dermatology · 2003
    19. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    20. Expression of ΔNLef1 in Mouse Epidermis Results in Differentiation of Hair Follicles into Squamous Epidermal Cysts and Formation of Skin Tumors Development · 2002
    21. Noggin Is Required for Induction of the Hair Follicle Growth Phase in Postnatal Skin The FASEB Journal · 2001
    22. Tcf3 and Lef1 Regulate Lineage Differentiation of Multipotent Stem Cells in Skin Genes & Development · 2001
    23. Deregulated Expression of c-Myc Depletes Epidermal Stem Cells Nature Genetics · 2001
    24. C-Myc Activation in Transgenic Mouse Epidermis Results in Mobilization of Stem Cells and Differentiation of Their Progeny Current Biology · 2001
    25. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    26. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000
    27. Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation Development · 1999
    28. WNT Signaling in the Control of Hair Growth and Structure Developmental biology · 1999
    29. The Secret Life of the Hair Follicle Trends in genetics · 1992