Injectable Therapy for Androgenetic Alopecia: A Systematic Review

    January 2026 in “ Dermatologic Surgery ”
    Jacob Beer, Tanya Boghosian, Hannah Mendez, Mira Sayegh, Nazar Boghosian, Antonella Tosti
    TLDR Injectable therapy, especially with dutasteride, may help with hair loss, but more research is needed.
    Injectable therapy for androgenetic alopecia (AGA) shows potential cosmetic benefits, particularly with the use of dutasteride, according to a systematic review of 30 studies, including 7 interventional, 11 observational, and 12 descriptive reports. The review highlights the use of multivitamin and peptide formulations, dutasteride, minoxidil, bicalutamide, growth factors, and finasteride, with varied techniques in needle type, depth, and dosing schedules. While outcomes such as increased hair density and stabilization of shedding were reported, adverse events like paradoxical alopecia and scarring were generally mild. However, the evidence is limited by small sample sizes, variable protocols, and short follow-up periods, indicating a need for standardized randomized trials before injectable therapy can be routinely recommended for AGA.
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