Effectiveness of Injectable Platelet-Rich Fibrin Therapy in Alopecia and Facial Rejuvenation: A Systematic Review

Injectable platelet-rich fibrin (PRF) therapy shows promise in treating androgenetic alopecia and enhancing facial esthetics, as evidenced by a systematic review of seven studies involving 130 patients. For alopecia, three studies reported noticeable improvements in hair density and growth. For facial rejuvenation, four studies demonstrated moderate to significant improvements in skin texture, elasticity, and reduction in wrinkles, confirmed by both subjective assessments and objective measurements. Despite these positive outcomes, further research with larger sample sizes, control groups, and longer follow-ups is needed to validate these findings and establish standardized treatment protocols.