Disturbance of Immune Microenvironment in Androgenetic Alopecia Through Spatial Transcriptomics
August 2024
in “
International Journal of Molecular Sciences
”
androgenetic alopecia spatial transcriptomics immune microenvironment infundibulum hair follicles immune cell clusters CD4+ T cells peri-infundibular immune infiltration gene set enrichment cellular deconvolution differential expression protein-protein interaction networks upstream regulator analysis AGA immune cell disruptions immune signatures immune dysregulation
Studysummary The study investigated immune cell patterns around the hair follicle infundibulum in androgenetic alopecia, revealing significant differences in immune signatures between patients with AGA and control donors, specifically noting an enrichment of CD4 cells in the patient group.
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