Amlodipine Topical Cream: An Effective Hair Growth Promoter for an Alopecia Mouse Model via VEGF-Mediated Angiogenesis and Vasodilation

March 2026 in “ Archives of Dermatological Research ”

Zainab Azal Mahdi, Ahmed Rahmah Abu-Raghif, Samer Salim Shahooth, Kholod Abbas Ali, Raid M. Al Abood, Ammar S. Al Khafaji, Hayder Ridha-Salman

The study explores the impact of amlodipine topical cream on hair growth in an alopecia mouse model, revealing that it promotes hair growth through VEGF-mediated angiogenesis and vasodilation. This suggests that amlodipine could serve as a potential treatment for hair loss by improving blood flow and nutrient delivery to hair follicles. The research underscores the importance of VEGF in hair growth and proposes that targeting angiogenesis pathways may be advantageous in treating alopecia.

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