The Effect of Cilostazol on Hair Growth: A Novel Therapeutic Option for the Treatment of Hair Loss

The document presents a study on the effects of Cilostazol, a phosphodiesterase3 (PDE3) inhibitor, on hair growth, suggesting it as a potential treatment for hair loss. The study found that Cilostazol significantly enhanced the viability of human dermal papilla cells and increased phosphorylated extracellular signal-regulated kinase (ERK) levels. It also promoted hair shaft elongation and increased proliferation of matrix keratinocytes in hair follicle organ culture. Furthermore, topical application of Cilostazol on mice accelerated the induction of anagen hair, the growth phase of the hair cycle. These results indicate that Cilostazol promotes hair growth and could be an alternative therapeutic option for alopecia. The number of people or subjects involved in the study is not mentioned in the provided text.