From Eye Care to Hair Growth: Bimatoprost
April 2024
in “Pharmaceuticals”
TLDR Bimatoprost helps with hair growth and eye conditions but can be costly and have side effects.
Bimatoprost, originally developed for eye care, has shown potential in promoting hair growth and treating alopecia and hypotrichosis by stimulating the hair cycle and prolonging the growth phase. It's also effective in reducing intraocular pressure (IOP), making it a first-line treatment for glaucoma and ocular hypertension. Studies have shown its efficacy for up to three years with minimal tolerance reports. Bimatoprost, often combined with timolol, has been found to be more effective in mean IOP control than other combinations. However, it's associated with higher costs and side effects such as ocular hyperemia, human corneal endothelium cytotoxicity, and sunken eyelids. Despite these, it's considered safe for breastfeeding mothers and has been approved by the FDA for hair growth treatment. Future perspectives include exploring novel delivery systems to enhance drug efficacy and patient comfort.
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Cited in this study
research The Role of Fractional Laser-Assisted Drug Delivery in Enhancing the Efficacy of Topical Bimatoprost Solution in the Treatment of Alopecia Areata: An Intra-Patient Comparative Randomized Clinical Trial
Using a laser with bimatoprost solution works better for hair regrowth in alopecia areata than bimatoprost alone.
research Comparative Study of the Efficacy and Safety of Topical Minoxidil 2% Versus Topical Bimatoprost 0.01% Versus Topical Bimatoprost 0.03% in Treatment of Eyebrow Hypotrichosis: A Randomized Controlled Trial
Bimatoprost 0.03% is as effective as minoxidil 2% for eyebrow growth.
research Prevention and Treatment of Chemotherapy-Induced Alopecia: What Is Available and What Is Coming?
Scalp cooling is the only FDA-approved method to prevent hair loss from chemotherapy, but other treatments like minoxidil and PRP are being tested.
research The Efficacy of Topical Prostaglandin Analogs for Hair Loss: A Systematic Review and Meta-Analysis
Topical prostaglandin analogs may help with hair growth but more research is needed.
research Combined Microneedling With Topical Vitamin D3 or Bimatoprost Versus Microneedling Alone in the Treatment of Alopecia Areata: A Comparative Randomized Trial
research Bimatoprost Versus Clobetasol Propionate in Scalp Alopecia Areata: A Prospective Non-Randomized Open-Label Clinical Trial
Bimatoprost and clobetasol are both effective for scalp hair loss, but bimatoprost works faster, has fewer side effects, and grows more colored hair.
research The Physiological and Pharmacological Roles of Prostaglandins in Hair Growth
research Preparation of Topical Bimatoprost with Enhanced Skin Infiltration and In Vivo Hair Regrowth Efficacy in Androgenic Alopecia
Bimatoprost cream can help regrow hair in baldness.
research Treatments for alopecia areata: A systematic review and network meta‐analysis
Some treatments like pentoxifylline with topical corticosteroids might work for alopecia areata, but more research is needed to find the best one.
research Phosphodiesterase inhibitors and prostaglandin analogues in dermatology: A comprehensive review
Certain drugs are effective for skin conditions like psoriasis, vitiligo, and hair loss.
research Prevention and Treatment of Chemotherapy-Induced Alopecia
Scalp cooling can help prevent hair loss from chemotherapy, but treatment should be tailored to the individual and more research is needed.
research Efficacy of non-surgical treatments for androgenetic alopecia in men and women: a systematic review with network meta-analyses, and an assessment of evidence quality
Minoxidil and finasteride work best for hair loss; more research needed.
research Harnessing the Power of Regenerative Therapy for Vitiligo and Alopecia Areata
Regenerative therapies show promise for treating vitiligo and alopecia areata.
research Efficacy and Safety of Bimatoprost 0.01% for the Treatment of Eyebrow Hypotrichosis
Bimatoprost 0.01% effectively and safely improves eyebrow growth.
research <p>Analysis of Bimatoprost-Induced changes on Rabbits eyelash Follicle: Clinical and Electron microscopic study</p>
Bimatoprost eye drops make rabbit eyelashes longer, thicker, and darker, and increase the number of lashes without causing inflammation.
research Eyebrow growth pattern analysis in patients with eyebrow hypotrichosis after receiving topical treatment: A retrospective study
Topical bimatoprost 0.01% improves eyebrow density and diameter, especially at the tail.
research Comparison of the efficacy and safety of using 0.01% versus 0.03% bimatoprost for the treatment of eyebrow hypotrichosis: A randomized, double‐blind, split‐face, comparative study
Both 0.01% and 0.03% bimatoprost safely improve eyebrow fullness, with a patient preference for the 0.03% concentration.
research HMGB1 promotes hair growth via the modulation of prostaglandin metabolism
A protein called HMGB1 helps hair grow by affecting prostaglandin metabolism.
research Laser-assisted drug delivery for the treatment of androgenetic alopecia: ablative laser fractional photothermolysis to enhance cutaneous topical delivery of platelet-rich plasma — with or without concurrent bimatoprost and/or minoxidil
research New drugs under investigation for the treatment of alopecias
New treatments for hair loss show promise, but more research is needed to confirm their safety and effectiveness.
research Guidelines for the diagnosis and treatment of male-pattern and female-pattern hair loss, 2017 version
Use finasteride, dutasteride, and minoxidil for hair loss treatment.
research Fractional Resurfacing and Topical Bimatoprost for the Treatment of Laser Induced Postinflammatory Hypopigmentation on the Lower Extremities
The combination therapy improved skin pigmentation.
research Topical Treatment of Eyebrow Hypotrichosis with Bimatoprost 0.03% Solution: Case Report and Literature Review
Bimatoprost 0.03% solution effectively promotes eyebrow growth.
research Therapeutic potential of bimatoprost for the treatment of eyebrow hypotrichosis
Bimatoprost is safe and effective for improving eyebrow hair.
research Pathogenesis and treatment options for chemotherapy‐induced alopecia: a systematic review
Scalp cooling is the most effective FDA-approved method to prevent chemotherapy-induced hair loss, but more research is needed for other treatments.
research Determination of illegal adulteration of dietary supplements with synthetic hair-growth compounds by UPLC and LC-Q-TOF/MS
The new method accurately detects illegal hair-growth drugs in dietary supplements.
research Bimatoprost for the treatment of eyelash, eyebrow and scalp alopecia
Bimatoprost is promising for treating some types of hair loss but needs more testing for androgenetic alopecia.
research Topical medication instillation techniques for glaucoma
There is not enough evidence to know if different ways of putting in eye drops for glaucoma work better than others.
research Treating Alopecia Areata: Current Practices Versus New Directions
research Successful Treatment of Pediatric Alopecia Areata of the Scalp Using Topical Bimatoprost
A 9-year-old girl with alopecia areata had successful hair regrowth using bimatoprost after other treatments failed.
research An evaluation of the safety and efficacy of bimatoprost for eyelash growth in pediatric subjects
Bimatoprost is safe and improves eyelash growth in healthy kids but not in those with eyelash loss from chemotherapy or alopecia.
research Promising alternative clinical uses of prostaglandin F2α analogs: Beyond the eyelashes
Prostaglandin F2α analogs show promise for treating certain types of hair loss but need more research for other skin conditions.
research Long‐term safety and efficacy of bimatoprost solution 0·03% application to the eyelid margin for the treatment of idiopathic and chemotherapy‐induced eyelash hypotrichosis: a randomized controlled trial
Bimatoprost solution is effective and safe for long-term use in treating eyelash thinning.
research Bimatoprost versus Mometasone Furoate in the Treatment of Scalp Alopecia Areata: A Pilot Study
Bimatoprost was found to be safer and more effective than mometasone furoate for treating scalp hair loss.
research Hirsutism following the use of bimatoprost eyedrops for glaucoma
A woman got unwanted hair growth on her face from using bimatoprost eyedrops for glaucoma.
research Safety and Efficacy of Bimatoprost Solution 0.03% Topical Application in Patients with Chemotherapy-Induced Eyelash Loss
Bimatoprost is safe and effective for treating eyelash loss caused by chemotherapy.
research Female pattern alopecia: current perspectives
Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.
research Treatment of Eyebrow Hypotrichosis Using Bimatoprost: A Randomized, Double-Blind, Vehicle-Controlled Pilot Study
Bimatoprost effectively and safely improves eyebrow appearance.
research Clinical Management of Trichotillomania With Bimatoprost
Bimatoprost can help regrow eyelashes in people with trichotillomania.
research The biodisposition and hypertrichotic effects of bimatoprost in mouse skin
Bimatoprost increases hair growth in mice without breaking down into other substances.
research The prostamide‐related glaucoma therapy, bimatoprost, offers a novel approach for treating scalp alopecias
Bimatoprost, a glaucoma medication, may also help treat hair loss.
research Promising therapies for treating and/or preventing androgenic alopecia.
There are potential treatments for pattern baldness, but more research is needed to confirm their effectiveness.
research Topical bimatoprost for the treatment of eyebrow hypotrichosis.
Bimatoprost can help grow eyebrow hair.
research Novel treatment of female-pattern androgenetic alopecia with injected bimatoprost 0.03% solution.
research Eyelash Growth from Application of Bimatoprost in Gel Suspension to the Base of the Eyelashes
Bimatoprost gel makes eyelashes grow longer, but may cause side effects and should be monitored by an eye doctor.
research Bimatoprost in the treatment of eyelash hypotrichosis
Bimatoprost is effective for growing longer, thicker, and darker eyelashes.
research Management of hypotrichosis of the eyelashes: Focus on bimatoprost
Bimatoprost ophthalmic solution 0.03% safely and effectively increases eyelash growth when applied to the upper eyelid.
research Bimatoprost in the treatment of eyelash universalis alopecia areata
Bimatoprost helped eyelash growth in nearly half of the patients with a type of eyelash hair loss.