Analysis of Bimatoprost-Induced Changes on Rabbit Eyelash Follicle: Clinical and Electron Microscopic Study

December 2019 in “ Clinical ophthalmology ”

Khulood Muhammad Sayed, Engy Mohamed Mostafa, Amr Mounir, Nesreen G. Abd El-Haliem, Alahmady Hamad Alsmman

bimatoprost eyelash follicle epidermis hair shafts pigmentation follicular activity hair cycles Latisse

TLDR Bimatoprost eye drops make rabbit eyelashes longer, thicker, and darker, and increase the number of lashes without causing inflammation.

The study on 15 male rabbits over 4 weeks demonstrated that bimatoprost significantly increased eyelash length and density, with treated eyes showing an average length of 11.60±0.46 mm compared to 9.75±0.33 mm in control eyes. Electron microscopy revealed structural changes such as a thicker epidermis, more hair shafts per follicle, and increased pigmentation, all without inflammation. These findings suggested that bimatoprost could strengthen eyelashes and potentially prevent eyelash loss during chemotherapy by enhancing follicular activity and promoting new hair cycles.

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Research cited in this study

12 / 12 results

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Analysis of Bimatoprost-Induced Changes on Rabbit Eyelash Follicle: Clinical and Electron Microscopic Study

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research Topical Treatment of Eyebrow Hypotrichosis with Bimatoprost 0.03% Solution: Case Report and Literature Review

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research Eyelash Preservation During Chemotherapy and Topical Prostaglandin Therapy

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research Prostaglandin Metabolism in Human Hair Follicle

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research Prostaglandin-Induced Hair Growth

research Hypertrichosis and Increased Pigmentation of Eyelashes and Adjacent Hair in the Region of the Ipsilateral Eyelids of Patients Treated with Unilateral Topical Latanoprost

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