Bimatoprost Versus Clobetasol Propionate in Scalp Alopecia Areata: A Prospective Non-Randomized Open-Label Clinical Trial

    January 2023 in “ Indian Dermatology Online Journal ”
    Mohan Bhusal, Shristi Bhattarai, Binita Thapa, PrashannaR Shrestha, G. E. C. H. Vidya Sagar
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    TLDR Bimatoprost and clobetasol are both effective for scalp hair loss, but bimatoprost works faster, has fewer side effects, and grows more colored hair.
    The non-randomized comparative clinical trial involved 50 patients and compared the efficacy and safety of topical bimatoprost 0.01% solution with the standard treatment topical steroid (clobetasol propionate 0.05% cream) in treating scalp alopecia areata (AA). After 12 weeks, both treatments showed no significant difference in hair regrowth. However, bimatoprost had fewer side effects, a more rapid response, and resulted in the growth of more pigmented hairs. Therefore, while both treatments are effective, bimatoprost may have certain advantages over clobetasol in treating AA.
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