Randomized Comparison of Topical Betamethasone Valerate Foam, Intralesional Triamcinolone Acetonide, and Tacrolimus Ointment in Management of Localized Alopecia Areata

January 2011 in “ International journal of trichology ”

C M Kuldeep, Himanshu Singhal, Ashok Kumar Khare, Asit Mittal, Lalit Gupta, Anubhav Garg

TLDR Intralesional triamcinolone acetonide is the most effective treatment for localized alopecia areata.

The study compared the effectiveness of topical betamethasone valerate foam, intralesional triamcinolone acetonide, and tacrolimus ointment in treating localized alopecia areata (AA) in 78 patients over 12 weeks. Results showed that intralesional triamcinolone acetonide led to the best hair regrowth (>75%, HRG IV) in 60% of patients, followed by betamethasone valerate foam with 53.6%, while tacrolimus ointment showed no significant regrowth. Mild side effects were reported with betamethasone valerate foam and tacrolimus. The study concluded that intralesional triamcinolone acetonide was the most effective treatment for localized AA.

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