48 citations
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June 1988 in “PubMed” In this study, minoxidil sulfate was found to relax norepinephrine-induced contractions in rabbit mesenteric arteries, possibly by acting as a K+ channel agonist, but it did not relax K+-induced contractions.
47 citations
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October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
1 citations
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June 2021 in “General physiology and biophysics” In this study, minoxidil-induced vasodilation in rat aorta was found to be mediated by ATP-sensitive potassium channels and nitric oxide pathways, but was not significantly altered by lipid emulsion pretreatment.
1 citations
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May 1987 in “The Lancet” Topical minoxidil may help hair growth by improving blood flow to hair follicles.
1 citations
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June 2023 in “Frontiers in Pharmacology” This study found that hydralazine and minoxidil, two direct vasodilators, may worsen abdominal aortic aneurysm progression by increasing aortic degeneration and inflammation.